April, 2008
Question: How do you administer Vancomycin 1gm IV?
Answer: Reconstitute a 1gm vial and then add to 250ml NSS. Infuse over at least 60 minutes.
Extra credit: What will occur if Vancomycin is run too rapidly?
Answer:
Red man syndrome may occur if the infusion is too rapid. It is not an allergic reaction, but may be characterized by hypotension and/or a maculopapular rash appearing on the face, neck, trunk, and/or upper extremities. If this should occur, slow the infusion rate to over 11/2 to 2 hours and increase the dilution volume. Reactions are often treated with antihistamines and steroids.